Our aim is to provide a forum for the exchange of ideas related to neuropelveology, and we would like to invite you to join us in our mission. The International Society of Neuropelveology (ISON) was founded by several individuals united by a common interest in the expanding field of neuropelveology. The ISON will provide the essential infrastructure and organizational framework for the support and development of neuropelveological education and research worldwide.

Definition of neuropelveology:
“the branch of medicine that deals with pathologies of the pelvic nerves and plexuses and with pelvic and spinal pathologies involving the pelvic nerves and plexuses in order to improve sensory and motor functions of the impaired pelvic nervous system through appropriate clinical diagnosis and laparoscopic neuro-functional procedures” Marc Possover



What luck to have experienced two revolutions! More than 20 years ago, when I was still a young gynecologist, I was lucky enough to be an active witness – and not just a passive observer – at the birth of laparoscopic gyneco-oncology. My first laparoscopic lymphadenectomy took place in 1992 with Denis Querleu, and the second with Joel M. Childers. I learnt radical vaginal surgery from Daniel Dargent in 1993. Back then there were no limits, and the goal was to make everything possible via laparoscopy. Thanks to new developments in surgical instruments and video technology, the radicality of laparoscopic pelvic surgery has been greatly improved. One of the side effects, so to speak, was unfortunately an increase in functional morbidity. To reduce or even prevent the latter, instead of reducing radicality we returned to the roots of surgery: the beloved discipline of anatomy. It very quickly emerged that laparoscopy is the ideal tool for improving our understanding of, learning about and investigating pelvic neuro-anatomy. Textbooks and cadaver dissections have helped to significantly improve our knowledge of topographical anatomy and have helped us to apply these skills in our laparoscopic interventions. In order to better determine the function of the nerves intraoperatively, we introduced a technique of intraoperative nerve stimulation, known as the LANN technique. This marked the birth of neuropelveology. Improvements over the years have constantly benefited surgery. Neuropelveology is the key. It has led to nerve-sparing methods in gynecology. Laparoscopic interventions have since been on the increase and have a wide range of uses, from neurosurgery on the pelvic nerves to neuro-functional procedures in neuroprosthetics in pelvic nerves, known as the LION procedure.

This development inevitably increased awareness of the fact that pelvic nerve diseases are much more common than previously assumed. Nerves do not reside as inert structures; they begin to tell their own stories. What was missing, however, was a method for diagnosing such diseases. Consequently, there has been rising interest in diagnostic neurology and neuro-urology. Diagnostics in neuropelveology result from the synthesis of information gained from various medical disciplines (gynecology, neuro-urology, neurology, neurosurgery, etc.).

All these aspects pave the way for and are components of neuropelveology. Despite the immense amount of commitment and curiosity required, it is well worth the effort for our patients. Neuropelveology is attracting growing interest from an increasing number of experts from various disciplines – hopefully including you, honorable colleagues. The foundation stones of neuropelveology have been laid. Young neuropelveologists should remain critical, extend and broaden their knowledge, and time and again raise questions. The aim is to gain a better understanding of the functions and interactions of the pelvic nerves and plexuses, and to respect these and consequently improve the treatment of related diseases. Whether ISON is ultimately a “comet of the century” depends on us and, most of all, on the forthcoming generations of young and inquisitive medical professionals. Last but never least, let me express a sincere and honest thank you to our friends, the founding members and advisory board, who have invested time, health, money and a wealth of passion to bring life to the International Society of Neuropelveology.
Marc Possover



  • To establish the authoritative forum for communicating cutting edge research and practice issues in neuropelveology
  • The first global educational organization committed to neuropelveology
  • A not-for-profit organization


  • Promote the timely exchange and dissemination of new neuropelveology-related knowledge and findings
  • Promote excellence in neuropelveological care worldwide
  • Develop an authoritative forum that builds international and regional consensuses on therapy and research in neuropelveology
  • Inspire young investigators to engage in neuropelveology research
  • Involve multiple disciplines, with additional professional diversity anticipated as the Society grows
  • Promote international exchanges in which fellows and junior faculty spend time in other countries to learn how clinical research is conducted around the world
  • Increase the number of mentored publications and recognize good mentors
  • Coordinate multicenter clinical trials
  • Collect reliable data on current methods and standards